Wednesday, March 04, 2009

Safety First

The Medicines and Healthcare products Regulatory Agency (MHRA) has published Drug Safety Update for March 2009 (PDF).

This issue contains a hot topic about the public perception of herbal medicines, a yellow card update that focusses on the rare adverse drug reaction of progressive multifocal leukoencephalopathy (PML) and drug safety updates in the following areas:

Methylphenidate: updated guidance on safe and effective use in ADHD
Atomoxetine: risk of psychotic or manic symptoms
Antipsychotics: use in elderly patients with dementia
Exenatide (Byetta): risk of severe pancreatitis and renal failure
Bisphosphonates: atypical stress fractures

Hat tip: http://www.prescriber.org.uk/

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