The UK Medicines and Healthcare products Regulatory Agency (MHRA) have issued a press release about NSAIDs and their risks and benefits.
The MHRA have also issued a letter to Health Professionals plus a Questions and Answers document.
The main point of interest from the review is contained in the MHRA letter to health professionals. The review has found that diclofenac (particularly at 150mg/day) and ibuprofen (at high dose - 2400mg/day) may carry a small thrombotic risk.
This same risk has not been established for naproxen.
Hat tip: the excellent Prescribing Advice for GPs
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