Big Pharma's Big Problem - "the status quo is not an option!"

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The threat to Big Pharma is real - the nation's drugmakers stand to lose nearly seven percent of their sales to drugs going off patent this year - and more CEOs who don't get ahead of the problem could end up losing their jobs.

"Three of the six U.S. pharma company CEOs have been terminated over the last year, and new managements understand that the status quo is NOT an option," Barbara Ryan, analyst for Deutsche Bank North America, wrote in a recent note to clients.

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