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The brand name of a popular Canadian over-the-counter medication containing aspirin, caffeine, and 8 mg of codeine per tablet is 222. It is widely available throughout most of Canada. The use of codeine in the United States is more restrictive.
It is a prescription medication in most states, although several states do permit non-prescription use when it is monitored by a licensed pharmacist. The popularity of mail order pharmacy and the proximity of the U.S.-Canadian border have led to the availability of 222’s and the unrestricted use of this medication in the U.S.
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