Drug development is a lottery-ticket business, and Lisa Conte has been scratching for a long time. Her quest has spanned two decades, two initial public offerings, a stock delisting, a bankruptcy and an ultramarathon of fundraising to pay for rigorous testing required by the Food & Drug Administration. "You have to think that you're going to make a boatload of money--this isn't charity," says Conte, 51.
You also have to be an extraordinarily savvy saleswoman. Since 1989 Conte, a lithe, high-energy networker, has burned through $200 million in funding--much of it from wealthy individuals--to develop prescription drugs derived from plants and aimed at a range of ailments, from diabetes to diarrhea.
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