Saturday, April 30, 2011

BBC NEWS | Panorama | Reputations for sale?

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Fiona Godlee is the editor in chief of the British Medical Journal and has written this article about Secrets of the Drugs Trials.
Panorama's account of GlaxoSmithKline's successful attempts to market Seroxat for use in children, despite the fact that its own published trial found evidence of serious adverse effects and failed to show benefit, is fascinating but depressingly familiar.
What is even more depressing is that such behaviour is still so widely tolerated within medicine.
There has been no shortage of outcry or official condemnation - including clear statements from the World Association of Medical Editors, the International Committee of Medical Journal Editors, and industry itself through its Good Publication Practice guidelines - that undeclared conflicts of interest and ghost writing are unacceptable.
But, you might reasonably ask, what use are such huffings and puffings in the face of the individual rewards on offer from drug companies.
Let's be clear what is and is not acceptable. There is nothing wrong with getting help from medical writers, provided they and their source of funding are clearly acknowledged.
Nor is there anything wrong with academics or clinicians working with industry, provided they remain personally accountable for everything they say.
What is clearly wrong is writers, academics, or clinicians concealing under their coat tails an army of company spin doctors intent on distorting the scientific record.
Legislation is not going to happen soon - the powerful industry lobby will make sure of that. Regulation is still inadequate.
So what can we do to change the blind-eye culture of medicine? In the interests of patients and professional integrity I suggest intolerance and exposure.
We shouldn't have to rely on investigative journalists to ask the difficult questions.
So at meetings, why not slow hand clap any speaker who does not begin their talk with a sentence or slide declaring their conflicts of interest?
And if journals discover authors who are guests on their own papers, they should report them to their institution, admonish them in the journal and probably retract the paper.
Reputations for sale are reputations at risk. We need to make that risk so high it's not worth taking."

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