The Annals of Internal Medicine has published a paper reviewing the available evidence to support the currently proposed treatment goals for lipid levels.
Treatment goals for total cholesterol and low-density lipoprotein have been lowered in recent years in America and the United Kingdom. Despite these reductions in the targets the authors of this review found no high-quality evidence to support the targets. They also conclude that there is no reason that evidence could not be produced very quickly from a cohort analysis of large clinical trials such as the Heart Protection Study (HPS).
Aggressively pursuing lower lipid targets is not supported by high quality evidence at this time.
In the first instance clinicians should ensure that patients are prescribed a cost-effective statin as per previous recommendations.
Hat tip: Prescribing Advice for GPs
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