Tuesday, April 06, 2010

Are Novartis after Alexion?

You tell me!

The rumor.

An interesting press release from Feb this year!

Why Alexion?

Soliris® (eculizumab), the company's first product, is approved for the treatment of patients with paroxysmal nocturnal hemoglobinuria (PNH)1, a progressive and life-threatening disease characterized by the excessive destruction of red blood cells (hemolysis).2,3 Soliris is the only treatment for PNH that reduces hemolysis.1

PNH is rare enough for Alexion to charge $400,000 a patient.

Now indication number two should have pivotal data by the end of the year. This would bring in another group of patients, who will pay at least $400,000 a year to get the drug for atypical hemolytic uremic syndrome (aHUS); they need more drug, about 50% more drug, than PNH patients. Every patient in Phase III for PNH benefited and the p-value was incredibly statistically significant. Alexion will add on country after country over the course of this year, ending with an important Japanese approval, and so it's a revenue/EPS powerhouse story.


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