For instance, some investigators, such as Ronald Duman of Yale University, are focusing on finding compounds that will kick in more quickly in our bodies. Duman and his colleagues are trying to learn lessons from ketamine, an anesthetic and painkiller that is also sold illicitly under the name "Special K." The group has shown in rats that ketamine rapidly causes neurons to make new contacts with one another and, apparently by so doing, produces antidepressant effects. Based on an understanding of the molecular basis of those changes, the researchers are now looking for safer agents that operate in a similar way.
Wednesday, March 07, 2012
Faster-Acting Experimental Antidepressants Show Promise
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